Staff

Principal Investigator
Associate Professor Zaid Abassi
Lab Managers
Aviva Kabala
Safa Kananeh
Students

Thesis in Progress
M.Sc.

  1. Yara Kinanaeh, MSc student expected graduation 2019. The Expression of the Enzyme Corin in the Lungs In Health and Disease.
  2. Dalit Ben Hemo, MSc. student expected graduation 2019. Interplay between endothelin system and Heparanase in acute kidney injury.

PhD

  1. Emad Khoury PhD/MD student, expected graduation 2018. Hemodynamic and Molecular Mechanisms Underlying the Pathogenesis of Congestive Heart Failure: Role of Increased Intra-abdominal Pressure and Corin.
  2. Yoav Ben-Shahar, PhD student: Evaluation of signaling pathways involved in intestinal stem cell fate decision following intestinal ischemia-reperfusion in a rat.

Completed Theses
M.Sc.

  1. Bahaa Francis, M.Sc., 2004. Regulation of Renal and Intra-renal Hemodynamics: Involvement of the Endothelin System.
  2. Sammar Zeid, M.Sc., 2005. Cardiac and renal effects of omapatrilat, a vasopeptidase inhibitor, in rats with experimental congestive heart Failure
  3. Afif Yaacob, M.Sc., Alterations in Glomerular Slit Diaphragm Proteins in Experimental Nephrotic Syndrome: Effects of Different Anti-Proteinuric Therapies.
  4. Niroz Abu-Saleh, M.Sc., 2010. Renal ischemia in an experimental diabetic rat model: Role of nitric oxide, endothelin-1 and oxidative stress.
  5. Ilia Goltsman, M.Sc., 2011. Effects of Thiazolidinedione therapy on renal and cardiac function in rats with experimental congestive heart failure (Primary Supervisor: Prof. Joseph Winaver).
  6. Rana Basal, M.Sc. 2011. Detection of Chronic Heart Failure by Breath Samples. (Primary Supervisor: Prof. Hossam Haick).
  7. Micahel Davidson, M.Sc. Detecting Acute Kidney Injury through Exhaled Breath Using Nanosensors Array. (Primary Supervisor: Prof. Hossam Haick).
  8. Ravit Cohen, M. Sc. The involvement of ACE and ACE-2 in renal and cardiac dysfunction in rats with experimental heart failure.
  9. Aviad Rotenberg, MSc. The Effect of Heparanase on Sepsis and Acute Lung Injury (Primary Supervisor: Prof. Michael Kraus).
  10. Clara Khatib, MSc, Acute Kidney Injury: Pathogenesis and novel therapeutic approaches.
  11. Maya Kovalevsky, MSc. Student, expected graduation 2017. Monitoring cardiac function based on the work pressure time integral relationship in rats with volume-overload induced Heart Failure.

PhD

  1. Federico Pieruzzi, Ph.D., 1995. Expression of Renin-Angiotensin System Components in the Heart, Kidneys, and Lungs of Rats with Experimental Heart Failure. (Secondary Supervisor Prof. Harry Kieser-NIH, USA).
  2. Kalfon Limor PhD, 2008. Molecular Mechanisms and Signaling Pathways Mediating the Neuroprotective Action of the Green Tea Polyphenol, (-)-Epigallocatechin 3-Gallate (EGCG). (Primary Supervisor: Prof. Moussa Youdim).
  3. Danit Rozenfeld-Mechlovich, PhD, 2013. Molecular neuroprotective targets of the novel multifunction iron-chelating drug, M30 in experimental models of type 2 diabetes mellitus and Alzheimer disease, (Together with Prof. Moussa Youdim).
  4. Ilia Goltsman, PhD/MD student, 2013. Effects of Thiazolidinedione therapy on renal and cardiac function in rats with experimental congestive heart failure (Primary Supervisor: Prof. Joseph Winaver).
  5. Niroz Abu-Saleh, D.Sc., 2014. Effects of Increased Intra-Abdominal Pressure on Kidney Function in Health and Disease.

M.D. Thesis

  1. Ittai Fattal, M.D., October 2001: The influence of dietary salt on the expression of endothelin-converting enzyme-1 in the kidney. (Supervision with Prof. Joseph Winaver). (See ref. #45 in my list of publications).
  2. Anan Abbasi, M.D., January 2004: Involvement of aldosterone in myocardial fibrosis in experimental heart failure: Comparison with the contribution of angiotensin II. (See ref. #51 in my list of publications).
  3. Mahmoud Kial, M.D., September 2004: Effects of the Rho-kinase inhibitor, Y-27632, on renal function and hemodynamic parameters in rats with experimental congestive heart failure: Comparison with angiotensin II receptor antagonist.
  4. Hiba Shiekh, M.D., 2007: Effects of novel antidiuretic hormone receptor antagonists on renal function and cardiac hypertrophy in rats with experimental congestive heart failure. (This work was chosen as the best MD thesis in Israel in 2011). (See ref. #65 in my list of publications)
  5. Diana Faour, M.D., 2009: Effects of Everolimus on Urinary Protein Excretion in Normal Rats and on Proteinuria in Rats With Adriamycin-Induced Nephrotic Syndrome. (See ref. #86 in my list of publications)
  6. Matan Hemli M.D.,2014: Exhaled Volatile Organic Compounds As A Measurement Of Hemodialysis Dose Adequacy (See ref. in my list of publication 98).
  7. Suzan Naser M.D. 2014: Involvement of Heparanase In Acute Pancreatitis: Novel Therapeutic Approaches.

Basic Science for Physicians

  1. Suheir Assady, M.D., 1998. Differential effects of sera from normotensive and hypertensive pregnant women on Ca2+ metabolism in normal vascular smooth muscle cells. (Supervision with Prof. Jacob Green). (See ref. # 34 in my list of publication).
  2. Rima Gilman, M.D., 2000. The pathogenesis of pulmonary hypertension in hemodialysis patients via arterio-venous access. (Supervision with Dr. M. Yigla). (See ref. # 50 in my list of publication).
  3. Ali Yahia, M.D., 2003. Systemic and renal effects of omapatrilat, vasopeptidase inhibitor, in normal rats and animals with experimental heart failure. (See ref. # 46 in my list of publication).
  4. Zoya Kositch, M.D., 2004. Systemic and renal effects of omapatrilat (vasopeptidase inhibitor) in normal rats and animals with nephrotic syndrome. (See ref. # 52 in my list of publication).
  5. Ronit Tal M.D., 2007. The Effect of Vasopressin (AVP) on Pulmonary Edema Clearance. (Supervision with Prof. Zaher Azzam), (See ref. # 91 in my list of publication).
  6. Samer Khatib, M.D., 2008-9. Renal effects of endothelin inhibitors in normal rats and animals with experimental pneumoperitoneum. (See ref. # 63,69 in my list of publication).
  7. Gidon Berger, M.D., 2008-9. Effects of sepsis on lung edema clearance. (Supervision with Prof. Zaher Azzam). (see ref. # 91 in my list of publications). 
  8. Nabil Ghrayeb, M.D., 2010. Effects of pneumoperitoneum on renal function in rats with CHF. (see ref. # 90 in my list of publications).
  9. Elias Haddad, MD, Effects of pneumoperitoneum on renal function in rats with myocardial infarction. (see ref. # 90 in my list of publications).
  10. Mohammad Naffaa, MD, 2012. Effects of increased intra-abdominal pressure on renal function in rats with acute obstructive jaundice and hepatic cirrhosis. (see ref. # 93 in my list of publications).
  11. Wisam Abboud, MD 2014, Effects of pneumoperitoneum on renal function in rats with experimental DM as compared with normal rats.
  12. Ahmad Hassan, MD, 2015, Involvement of Heparanase in the Pathogenesis of Ischemic Acute Kidney Injury.
  13. Rabia Shekh Muhammad MD, 2016 The Involvement of Heparanase in Oxidative Stress and Atherosclerosis Progression in E0 Knockout Mice
  14. Elias Hellou, MD, 2016-7, The Impact of Age and Comorbidities on Acute Kidney Injury of Patients with renal cell carcinoma undergoing partial nephrectomy.
  15. Majdi Saadi, MD, 2017, The Interplay Between Heparanase enzyme and Endothelin in the Pathogenesis of Ischemic Acute Kidney Injury.
  16. Safi Khoury, MD, 2017, Impact of elevated intra-abdominal pressure (pneumoperitoneum) on kidney injury in normal rats and animals with congestive heart failure: Measurement of urinary neutrophil gelatinase associated lipocalin (uNGAL) as a biomarker of acute kidney injury.